Can one have health issues that would make enlightenment impossible?

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No. If this is your situation, what you should try to do is accept your health issues, rather than trying to fight them. Surrender to them.

It doesn’t mean that you should stop going to a doctor or take medication. That’s not what I mean. What I mean is psychological acceptance, stop thinking that your life would be better if you didn’t have them, comparing yourself with other people who don’t have them etc. Accept that they are here, that this is your experience and it’s the only experience you have. Don’t judge or compare.