Can Kundalini awakening be scientifically explained?

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Sure! Spiritual awakening happens in the mind. But the brain can be said to be a central hub of the vast and intricately connected nervous system which covers every inch of your body. They are inseparable. So, Kundalini awakening can be viewed as the whole of your neural system (not just the brain) slowly re-wiring itself into its natural, unconditioned state. It can be quite overwhelming at times, but it doesn’t have to be viewed as something mysterious. Of course, if you want to see it as mysterious, you will, and it’s not wrong, it’s just a matter of perception. All explanations and realizations during the unfolding are related to your current perception. So it doesn’t really matter how one views it when it happens, what’s important is to allow it to happen and know that your body is safe.